Version 5.4
Homo sapiens Protein: REXO1
Summary
InnateDB Protein IDBP-15057.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol REXO1
Protein Name REX1, RNA exonuclease 1 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000170168
InnateDB Gene IDBG-15055 (REXO1)
Protein Structure
UniProt Annotation
Function Seems to have no detectable effect on transcription elongation in vitro. {ECO:0000269PubMed:12943681}.
Subcellular Localization Nucleus {ECO:0000269PubMed:12943681}.
Disease Associations
Tissue Specificity Ubiquitously expressed. {ECO:0000269PubMed:12943681}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
Biological Process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR006055 Exonuclease
IPR012337 Ribonuclease H-like domain
IPR013520 Exonuclease, RNase T/DNA polymerase III
PFAM PF00929
PRINTS
PIRSF
SMART SM00479
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N1G1
PhosphoSite PhosphoSite-Q8N1G1
TrEMBL
UniProt Splice Variant
Entrez Gene 57455
UniGene Hs.601776
RefSeq NP_065746
HUGO HGNC:24616
OMIM 615201
CCDS CCDS32866
HPRD 15478
IMGT
EMBL AB032964 AC012615 BC032244
GenPept AAH32244 BAA86452

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca