Version 5.4
Homo sapiens Protein: EFHA1
Summary
InnateDB Protein IDBP-14562.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EFHA1
Protein Name EF-hand domain family, member A1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000371811
InnateDB Gene IDBG-14560 (EFHA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006851 mitochondrial calcium ion transport
GO:0051561 positive regulation of mitochondrial calcium ion concentration
GO:0051562 negative regulation of mitochondrial calcium ion concentration
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0034704 calcium channel complex
GO:1990246 uniplex complex
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IYU8
PhosphoSite PhosphoSite-Q8IYU8
TrEMBL
UniProt Splice Variant
Entrez Gene 221154
UniGene
RefSeq NP_689939
HUGO HGNC:31830
OMIM 610632
CCDS CCDS9297
HPRD 16852
IMGT
EMBL AK091907 AL136219 AL138680 BC031089 BC034965
GenPept AAH31089 AAH34965 BAC03769 CAH70136 CAH70594

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca