InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Zdhhc8

Summary

InnateDB Protein

IDBP-141148.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Zdhhc8

Protein Name

zinc finger, DHHC domain containing 8

Synonyms

D16H22S1738E; DHHC-8; E330009O14Rik; Op53c05; ZDHHCL1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000076224

InnateDB Gene

IDBG-141146 (Zdhhc8)

Protein Structure

UniProt Annotation

Function

Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1. {ECO:0000269PubMed:15184899}.

Subcellular Localization

Cytoplasmic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in brain cortex and hippocampus. {ECO:0000269PubMed:15184899}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016409	palmitoyltransferase activity
GO:0019706	protein-cysteine S-palmitoyltransferase activity

Biological Process

GO:0007275	multicellular organismal development
GO:0007626	locomotory behavior
GO:0008152	metabolic process
GO:0018345	protein palmitoylation

Cellular Component

GO:0005739	mitochondrion
GO:0005794	Golgi apparatus
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030659	cytoplasmic vesicle membrane
GO:0048471	perinuclear region of cytoplasm