InnateDB Protein
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IDBP-14088.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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VAMP1
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Protein Name
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vesicle-associated membrane protein 1 (synaptobrevin 1)
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Synonyms
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SPAX1; SYB1; VAMP-1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000355122
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InnateDB Gene
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IDBG-14084 (VAMP1)
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Protein Structure
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Function |
Involved in the targeting and/or fusion of transport vesicles to their target membrane.
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Subcellular Localization |
Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}.Isoform 2: Cytoplasmic vesicle membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}.Isoform 3: Mitochondrion outer membrane; Single-pass type IV membrane protein.
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Disease Associations |
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Tissue Specificity |
Nervous system, skeletal muscle and adipose tissue.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
12
[view]
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Protein-Protein |
8
[view]
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Protein-DNA |
4
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001388
Synaptobrevin
IPR016444
Synaptobrevin/Vesicle-associated membrane protein
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PFAM |
PF00957
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PRINTS |
PR00219
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PIRSF |
PIRSF005409
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P23763
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PhosphoSite |
PhosphoSite-P23763
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
6843
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UniGene |
Hs.20021
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RefSeq |
NP_954740
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HUGO |
HGNC:12642
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OMIM |
185880
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CCDS |
CCDS31731
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HPRD |
01716
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IMGT |
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EMBL |
AC005840
AF060538
BC023286
CH471116
CR542214
CR542231
CR749485
M36196
M36197
M36198
M36199
M36200
Z48924
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GenPept |
AAA60603
AAC28336
AAH23286
CAA88760
CAG47010
CAG47027
CAH18312
EAW88792
EAW88795
EAW88796
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