InnateDB Protein
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IDBP-133880.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Ube2e2
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Protein Name
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ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000075495
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InnateDB Gene
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IDBG-133878 (Ube2e2)
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Protein Structure
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Function |
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination (By similarity). Catalyzes the ISGylation of influenza A virus NS1 protein (By similarity). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 64 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
64 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2384997
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InterPro |
IPR000608
Ubiquitin-conjugating enzyme, E2
IPR016135
Ubiquitin-conjugating enzyme/RWD-like
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PFAM |
PF00179
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q91W82
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PhosphoSite |
PhosphoSite-Q91W82
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TrEMBL |
D3YW10
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UniProt Splice Variant |
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Entrez Gene |
218793
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UniGene |
Mm.408538
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RefSeq |
XP_006518072
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MGI ID |
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MGI Symbol |
Ube2e2
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OMIM |
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CCDS |
CCDS26838
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HPRD |
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IMGT |
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EMBL |
AC118006
AC121296
AC132459
BC016265
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GenPept |
AAH16265
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