InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MYO5C

Summary

InnateDB Protein

IDBP-12505.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYO5C

Protein Name

myosin VC

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000261839

InnateDB Gene

IDBG-12503 (MYO5C)

Protein Structure

UniProt Annotation

Function

May be involved in transferrin trafficking. Likely to power actin-based membrane trafficking in many physiologically crucial tissues.

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed chiefly in non-neuronal tissues. Particularly abundant in epithelial and glandular tissues including pancreas, prostate, mammary, stomach, colon and lung. {ECO:0000269PubMed:11870218}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003774	motor activity
GO:0003779	actin binding
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0005524	ATP binding

Biological Process

GO:0008152

metabolic process

Cellular Component

GO:0016459

myosin complex

Protein Structure and Domains

PDB ID

InterPro

IPR000048 IQ motif, EF-hand binding site
IPR001609 Myosin head, motor domain
IPR002710 Dilute
IPR018444 Dil domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00612
PF00063
PF01843

PRINTS

PR00193

PIRSF

SMART

SM00015
SM00242

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt