InnateDB Protein
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IDBP-12062.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GLDN
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Protein Name
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gliomedin
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000335196
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InnateDB Gene
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IDBG-12060 (GLDN)
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Protein Structure
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Function |
Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the nodes of Ranvier (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the nodes of Ranvier. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system. {ECO:0000269PubMed:16039564}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0005515
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protein binding
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GO:0086080
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protein binding involved in heterotypic cell-cell adhesion
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003112
Olfactomedin-like
IPR008160
Collagen triple helix repeat
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PFAM |
PF02191
PF01391
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PRINTS |
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PIRSF |
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SMART |
SM00284
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TIGRFAMs |
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Modification |
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SwissProt |
Q6ZMI3
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PhosphoSite |
PhosphoSite-Q6ZMI3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
342035
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UniGene |
Hs.708512
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RefSeq |
NP_861454
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HUGO |
HGNC:29514
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OMIM |
608603
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CCDS |
CCDS10140
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HPRD |
12267
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IMGT |
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EMBL |
AK172756
AY358144
BK001262
BX538105
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GenPept |
AAQ88511
BAD18742
CAD98018
DAA01143
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