Homo sapiens Protein: SIPA1L1
Summary
InnateDB Protein IDBP-10950.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIPA1L1
Protein Name signal-induced proliferation-associated 1 like 1
Synonyms E6TP1;
Species Homo sapiens
Ensembl Protein ENSP00000351352
InnateDB Gene IDBG-10948 (SIPA1L1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0031532 actin cytoskeleton reorganization
GO:0032317 regulation of Rap GTPase activity
GO:0032861 activation of Rap GTPase activity
GO:0043547 positive regulation of GTPase activity
GO:0048013 ephrin receptor signaling pathway
GO:0048167 regulation of synaptic plasticity
GO:0050770 regulation of axonogenesis
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0061001 regulation of dendritic spine morphogenesis
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0014069 postsynaptic density
GO:0030054 cell junction
GO:0043197 dendritic spine
GO:0045211 postsynaptic membrane
Protein Structure and Domains
PDB ID
InterPro IPR000331 Rap GTPase activating protein domain
IPR001478 PDZ domain
IPR021818 Protein of unknown function DUF3401
PFAM PF02145
PF00595
PF13180
PF11881
PRINTS
PIRSF
SMART SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O43166
PhosphoSite PhosphoSite-O43166
TrEMBL G3V4Z3
UniProt Splice Variant
Entrez Gene 26037
UniGene Hs.736869
RefSeq NP_001271175
HUGO HGNC:20284
OMIM
CCDS CCDS61491
HPRD 11559
IMGT
EMBL AB007900 AC004900 AC004968 AC004974 AC005476 AC005994 AF090989 AF090990 AK122930 AL391735
GenPept AAC83179 AAD12543 AAD12544 BAA23712