InnateDB Protein
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IDBP-10521.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLC10A1
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Protein Name
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solute carrier family 10 (sodium/bile acid cotransporter family), member 1
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Synonyms
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NTCP;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000216540
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InnateDB Gene
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IDBG-10519 (SLC10A1)
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Protein Structure
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Function |
The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.
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Subcellular Localization |
Membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0008508
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bile acid:sodium symporter activity
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GO:0015125
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bile acid transmembrane transporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR002657
Bile acid:sodium symporter
IPR004710
Bile acid transporter
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PFAM |
PF01758
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q14973
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PhosphoSite |
PhosphoSite-Q14973
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TrEMBL |
Q9UK36
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UniProt Splice Variant |
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Entrez Gene |
6554
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UniGene |
Hs.952
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RefSeq |
NP_003040
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HUGO |
HGNC:10905
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OMIM |
182396
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CCDS |
CCDS9797
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HPRD |
01672
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IMGT |
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EMBL |
AF184235
AY544127
BC069799
BC069822
BC074724
BC126298
BC136355
CH471061
L21893
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GenPept |
AAA36381
AAD56541
AAH69799
AAH69822
AAH74724
AAI26299
AAI36356
AAT11158
EAW81011
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