InnateDB Protein
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IDBP-10099.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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POLDIP3
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Protein Name
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polymerase (DNA-directed), delta interacting protein 3
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000252115
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InnateDB Gene
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IDBG-10097 (POLDIP3)
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Protein Structure
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Function |
Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex. {ECO:0000269PubMed:18423201, ECO:0000269PubMed:22928037}.
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Subcellular Localization |
Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
19
[view]
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Protein-Protein |
19
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000504
RNA recognition motif domain
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PFAM |
PF00076
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PRINTS |
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PIRSF |
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SMART |
SM00360
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BY77
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PhosphoSite |
PhosphoSite-Q9BY77
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TrEMBL |
Q96DI9
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UniProt Splice Variant |
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Entrez Gene |
84271
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UniGene |
Hs.743592
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RefSeq |
NP_115687
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HUGO |
HGNC:23782
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OMIM |
611520
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CCDS |
CCDS14038
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HPRD |
17875
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IMGT |
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EMBL |
AB055760
AK291623
AK291774
AL160111
AL160112
AY422990
BC001488
BC049840
BC056912
BC095411
CR456456
DQ887818
Z93241
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GenPept |
AAH01488
AAH49840
AAH56912
AAH95411
AAQ94604
ABI74675
BAB33368
BAF84312
BAF84463
CAB77058
CAB77059
CAG30342
CAI19835
CAQ08413
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