Version 5.4
Homo sapiens Gene: MAN2B2
Summary
InnateDB Gene IDBG-9001.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAN2B2
Gene Name mannosidase, alpha, class 2B, member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000013288
Encoded Proteins
IDBP-9003
mannosidase, alpha, class 2B, member 2
IDBP-477459
mannosidase, alpha, class 2B, member 2
IDBP-473882
mannosidase, alpha, class 2B, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:6575175-6623362
Strand Forward strand
Band p16.1
Transcripts
ENST00000285599 ENSP00000285599
ENST00000504248 ENSP00000423129
ENST00000505907 ENSP00000426273
ENST00000504960
ENST00000510427
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004559 alpha-mannosidase activity
GO:0008270 zinc ion binding
GO:0015923 mannosidase activity
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006013 mannose metabolic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000029119
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
hsa00511
Other glycan degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.188464 Hs.623012 Hs.625918
RefSeq NM_015274
HUGO
OMIM
CCDS CCDS33951
HPRD 14355
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca