Homo sapiens Gene: ST13 | |||||||||||||||||||||
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Summary | |||||||||||||||||||||
InnateDB Gene | IDBG-8875.6 | ||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||
Gene Symbol | ST13 | ||||||||||||||||||||
Gene Name | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | ||||||||||||||||||||
Synonyms | AAG2; FAM10A1; FAM10A4; HIP; HOP; HSPABP; HSPABP1; P48; PRO0786; SNC6 | ||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||
Ensembl Gene | ENSG00000100380 | ||||||||||||||||||||
Encoded Proteins |
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
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Protein Structure | |||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||
Summary |
The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that is a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008] The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013] |
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Gene Information | |||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||
Genomic Location | Chromosome 22:40824535-40857022 | ||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||
Band | q13.2 | ||||||||||||||||||||
Transcripts | |||||||||||||||||||||
Interactions | |||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 46 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||
NETPATH | |||||||||||||||||||||
REACTOME | |||||||||||||||||||||
KEGG | |||||||||||||||||||||
INOH | |||||||||||||||||||||
PID NCI | |||||||||||||||||||||
Cross-References | |||||||||||||||||||||
SwissProt | |||||||||||||||||||||
TrEMBL | F6VDH7 | ||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||
Entrez Gene | 6767 | ||||||||||||||||||||
UniGene | Hs.511834 Hs.567697 Hs.712713 Hs.713517 Hs.714861 | ||||||||||||||||||||
RefSeq | NM_001278589 NM_003932 | ||||||||||||||||||||
HUGO | HGNC:11343 | ||||||||||||||||||||
OMIM | 606796 | ||||||||||||||||||||
CCDS | CCDS14006 | ||||||||||||||||||||
HPRD | 08426 | ||||||||||||||||||||
IMGT | |||||||||||||||||||||
EMBL | Z98048 | ||||||||||||||||||||
GenPept | |||||||||||||||||||||
RNA Seq Atlas | 6767 | ||||||||||||||||||||