Version 5.4
Homo sapiens Gene: TNRC6B
Summary
InnateDB Gene IDBG-8635.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TNRC6B
Gene Name trinucleotide repeat containing 6B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100354
Encoded Proteins
IDBP-8637
trinucleotide repeat containing 6B
IDBP-8639
trinucleotide repeat containing 6B
IDBP-293363
trinucleotide repeat containing 6B
IDBP-377528
trinucleotide repeat containing 6B
IDBP-377530
trinucleotide repeat containing 6B
IDBP-377545
trinucleotide repeat containing 6B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:40044817-40335808
Strand Forward strand
Band q13.1
Transcripts
ENST00000301923 ENSP00000306759
ENST00000335727 ENSP00000338371
ENST00000402203 ENSP00000384795
ENST00000454349 ENSP00000401946
ENST00000441751 ENSP00000397491
ENST00000446273 ENSP00000409429
ENST00000489500
ENST00000497559
ENST00000467658
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 43 [view]
Protein-Protein 43 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006417 regulation of translation
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007219 Notch signaling pathway
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0010467 gene expression
GO:0031047 gene silencing by RNA
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0045087 innate immune response
GO:0048011 neurotrophin TRK receptor signaling pathway
GO:0048015 phosphatidylinositol-mediated signaling
GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000047888
View Gene Order
ENSBTAG00000021076
Not yet available
Pathways
NETPATH
REACTOME
REACT_75829
PIP3 activates AKT signaling pathway
REACT_147814
DAP12 signaling pathway
REACT_147694
DAP12 interactions pathway
REACT_12464
PI3K/AKT activation pathway
REACT_12578
GAB1 signalosome pathway
REACT_9417
Signaling by EGFR pathway
REACT_115961
PI3K events in ERBB4 signaling pathway
REACT_115596
Signaling by ERBB4 pathway
REACT_116008
PI3K events in ERBB2 signaling pathway
REACT_115755
Signaling by ERBB2 pathway
REACT_118568
Pre-NOTCH Transcription and Translation pathway
REACT_21270
PI-3K cascade pathway
REACT_9470
Signaling by FGFR pathway
REACT_111040
Signaling by SCF-KIT pathway
REACT_17025
Downstream signal transduction pathway
REACT_16888
Signaling by PDGF pathway
REACT_118699
Post-transcriptional silencing by small RNAs pathway
REACT_120736
Signaling by FGFR in disease pathway
REACT_120956
Cellular responses to stress pathway
REACT_169325
Oncogene Induced Senescence pathway
REACT_11061
Signalling by NGF pathway
REACT_115871
Signaling by EGFR in Cancer pathway
REACT_21272
Downstream signaling of activated FGFR pathway
REACT_172761
Ca2+ pathway pathway
REACT_118744
Pre-NOTCH Expression and Processing pathway
REACT_172694
beta-catenin independent WNT signaling pathway
REACT_11045
Signaling by Wnt pathway
REACT_163769
Role of LAT2/NTAL/LAB on calcium mobilization pathway
REACT_6802
Innate Immune System pathway
REACT_163936
Fc epsilon receptor (FCERI) signaling pathway
REACT_111102
Signal Transduction pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_169274
Cellular Senescence pathway
REACT_12056
NGF signalling via TRKA from the plasma membrane pathway
REACT_299
Signaling by NOTCH pathway
REACT_147723
PI3K/AKT Signaling in Cancer pathway
REACT_118773
Signaling by the B Cell Receptor (BCR) pathway
REACT_169436
Oxidative Stress Induced Senescence pathway
REACT_118638
Downstream signaling events of B Cell Receptor (BCR) pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
REACT_12472
Regulatory RNA pathways pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.372082 Hs.596407 Hs.602717 Hs.604403 Hs.609153 Hs.618125 Hs.624232 Hs.629307 Hs.710774
RefSeq NM_001024843 NM_001162501 NM_015088
HUGO
OMIM
CCDS CCDS46712 CCDS46713 CCDS54533
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca