Homo sapiens Gene: WIPI2 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-7422.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | WIPI2 | ||||||||||||||||||
Gene Name | WD repeat domain, phosphoinositide interacting 2 | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000157954 | ||||||||||||||||||
Encoded Proteins |
WD repeat domain, phosphoinositide interacting 2
WD repeat domain, phosphoinositide interacting 2
WD repeat domain, phosphoinositide interacting 2
WD repeat domain, phosphoinositide interacting 2
WD repeat domain, phosphoinositide interacting 2
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004 [PubMed 15602573]).[supplied by OMIM, Mar 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 7:5190188-5233826 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | p22.1 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||
SwissProt | Q9Y4P8 | ||||||||||||||||||
TrEMBL | A0A024R823 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 26100 | ||||||||||||||||||
UniGene | Hs.122363 Hs.700671 | ||||||||||||||||||
RefSeq | NM_015610 XM_006715685 NM_001033518 NM_001033519 NM_001033520 NM_001278299 NM_016003 | ||||||||||||||||||
HUGO | HGNC:32225 | ||||||||||||||||||
OMIM | 609225 | ||||||||||||||||||
CCDS | CCDS5339 CCDS34593 CCDS47531 CCDS47532 CCDS47533 | ||||||||||||||||||
HPRD | 15679 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AC093376 AF151808 AK024279 AL080155 AY691425 AY691426 BC004116 BC007596 BC021068 BC021200 CH471144 CR533530 | ||||||||||||||||||
GenPept | AAD34045 AAH04116 AAH07596 AAH21200 AAQ96865 AAQ96866 AAQ96867 AAV80761 AAV80762 BAG51284 CAB45746 CAG38561 EAW87326 EAW87327 EAW87328 | ||||||||||||||||||
RNA Seq Atlas | 26100 | ||||||||||||||||||