Version 5.4
Homo sapiens Gene: EIF3L
Summary
InnateDB Gene IDBG-7087.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EIF3L
Gene Name eukaryotic translation initiation factor 3, subunit L
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100129
Encoded Proteins
IDBP-7089
eukaryotic translation initiation factor 3, subunit L
IDBP-293738
eukaryotic translation initiation factor 3, subunit L
IDBP-376041
eukaryotic translation initiation factor 3, subunit L
IDBP-376044
eukaryotic translation initiation factor 3, subunit L
IDBP-376066
eukaryotic translation initiation factor 3, subunit L
IDBP-376067
eukaryotic translation initiation factor 3, subunit L
IDBP-376070
eukaryotic translation initiation factor 3, subunit L
IDBP-376073
eukaryotic translation initiation factor 3, subunit L
IDBP-811999
eukaryotic translation initiation factor 3, subunit L
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:37848868-37889407
Strand Forward strand
Band q13.1
Transcripts
ENST00000381683 ENSP00000371099
ENST00000406934 ENSP00000384634
ENST00000412331 ENSP00000416892
ENST00000439997 ENSP00000410576
ENST00000436452 ENSP00000398176
ENST00000414316 ENSP00000393822
ENST00000451427 ENSP00000390271
ENST00000450376 ENSP00000412349
ENST00000476955
ENST00000477256
ENST00000464790
ENST00000482600
ENST00000460638
ENST00000624234 ENSP00000485663
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 86 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 86 [view]
Protein-Protein 86 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
Cellular Component
GO:0001650 fibrillar center
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0016020 membrane
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033047
View Gene Order
ENSBTAG00000010790
Not yet available
Cross-References
SwissProt
TrEMBL C9JHP4
UniProt Splice Variant
Entrez Gene 51386
UniGene Hs.446852
RefSeq NM_001242923 NM_016091 XM_005261625
HUGO HGNC:18138
OMIM
CCDS CCDS13960 CCDS56230
HPRD 10932
IMGT
EMBL AL022311 Z97630
GenPept
RNA Seq Atlas 51386

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca