Version 5.4
Homo sapiens Gene: RHBDF1
Summary
InnateDB Gene IDBG-6861.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RHBDF1
Gene Name rhomboid 5 homolog 1 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000007384
Encoded Proteins
IDBP-6863
rhomboid 5 homolog 1 (Drosophila)
IDBP-361034
rhomboid 5 homolog 1 (Drosophila)
IDBP-361035
rhomboid 5 homolog 1 (Drosophila)
IDBP-361037
rhomboid 5 homolog 1 (Drosophila)
IDBP-361039
rhomboid 5 homolog 1 (Drosophila)
IDBP-361042
rhomboid 5 homolog 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:58059-76355
Strand Reverse strand
Band p13.3
Transcripts
ENST00000262316 ENSP00000262316
ENST00000428730 ENSP00000411508
ENST00000448893 ENSP00000406397
ENST00000417043 ENSP00000412218
ENST00000450643 ENSP00000408915
ENST00000419764 ENSP00000394427
ENST00000486045
ENST00000493647
ENST00000482904
ENST00000487201
ENST00000472390
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004252 serine-type endopeptidase activity
GO:0019838 growth factor binding
Biological Process
GO:0006508 proteolysis
GO:0008283 cell proliferation
GO:0015031 protein transport
GO:0016477 cell migration
GO:0042058 regulation of epidermal growth factor receptor signaling pathway
GO:0050708 regulation of protein secretion
GO:0050709 negative regulation of protein secretion
GO:0061136 regulation of proteasomal protein catabolic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020282
View Gene Order
ENSBTAG00000019805
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_022450 XM_005255494 XM_005255498 XM_006720921
HUGO
OMIM
CCDS CCDS32344
HPRD 07027
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca