Version 5.4
Homo sapiens Gene: PNN
Summary
InnateDB Gene IDBG-5267.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PNN
Gene Name pinin, desmosome associated protein
Synonyms DRS; DRSP; memA; SDK3
Species Homo sapiens
Ensembl Gene ENSG00000100941
Encoded Proteins
IDBP-5269
pinin, desmosome associated protein
IDBP-588488
pinin, desmosome associated protein
IDBP-594548
pinin, desmosome associated protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:39175183-39183218
Strand Forward strand
Band q21.1
Transcripts
ENST00000216832 ENSP00000216832
ENST00000553331 ENSP00000452217
ENST00000556530 ENSP00000452318
ENST00000554117
ENST00000554902
ENST00000557680
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 53 experimentally validated interaction(s) in this database.
Experimentally validated
Total 53 [view]
Protein-Protein 53 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005198 structural molecule activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007155 cell adhesion
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005882 intermediate filament
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0016020 membrane
GO:0016607 nuclear speck
GO:0030057 desmosome
GO:0035145 exon-exon junction complex
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020994
View Gene Order
ENSBTAG00000026995
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03013
RNA transport pathway
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G3V579
UniProt Splice Variant
Entrez Gene 5411
UniGene Hs.409965 Hs.595301 Hs.622102
RefSeq NM_002687
HUGO HGNC:9162
OMIM 603154
CCDS CCDS9671
HPRD 04401
IMGT
EMBL AL132639
GenPept
RNA Seq Atlas 5411

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca