Homo sapiens Gene: GABRG3 | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||||||
InnateDB Gene | IDBG-4418.5 | ||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||
Gene Symbol | GABRG3 | ||||||||||||||||
Gene Name | gamma-aminobutyric acid (GABA) A receptor, gamma 3 | ||||||||||||||||
Synonyms | |||||||||||||||||
Species | Homo sapiens | ||||||||||||||||
Ensembl Gene | ENSG00000182256 | ||||||||||||||||
Encoded Proteins |
gamma-aminobutyric acid (GABA) A receptor, gamma 3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
|
||||||||||||||||
Protein Structure | |||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||
Entrez Gene | |||||||||||||||||
Summary |
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012] |
||||||||||||||||
Gene Information | |||||||||||||||||
Type | Protein coding | ||||||||||||||||
Genomic Location | Chromosome 15:26971282-27541991 | ||||||||||||||||
Strand | Forward strand | ||||||||||||||||
Band | q12 | ||||||||||||||||
Transcripts | |||||||||||||||||
Interactions | |||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||||||||||||
Gene Ontology | |||||||||||||||||
Molecular Function |
|
||||||||||||||||
Biological Process |
|
||||||||||||||||
Cellular Component |
|
||||||||||||||||
Orthologs | |||||||||||||||||
Species
Mus musculus
|
Gene ID
Gene Order
|
||||||||||||||||
Pathways | |||||||||||||||||
NETPATH | |||||||||||||||||
REACTOME |
Ligand-gated ion channel transport pathway
GABA A receptor activation pathway
Transmembrane transport of small molecules pathway
Neuronal System pathway
GABA receptor activation pathway
Orphan transporters pathway
Ion channel transport pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
|
||||||||||||||||
KEGG |
Neuroactive ligand-receptor interaction pathway
|
||||||||||||||||
INOH | |||||||||||||||||
PID NCI | |||||||||||||||||
Cross-References | |||||||||||||||||
SwissProt | |||||||||||||||||
TrEMBL | H0YJP1 | ||||||||||||||||
UniProt Splice Variant | |||||||||||||||||
Entrez Gene | 2567 | ||||||||||||||||
UniGene | Hs.569475 Hs.740015 | ||||||||||||||||
RefSeq | NM_001270873 NM_033223 | ||||||||||||||||
HUGO | HGNC:4088 | ||||||||||||||||
OMIM | 600233 | ||||||||||||||||
CCDS | CCDS45195 CCDS59251 | ||||||||||||||||
HPRD | 02579 | ||||||||||||||||
IMGT | |||||||||||||||||
EMBL | AC104002 AC127511 AC135326 AC136896 AC144833 AC145436 EU606049 | ||||||||||||||||
GenPept | |||||||||||||||||
RNA Seq Atlas | 2567 | ||||||||||||||||