Version 5.4
Homo sapiens Gene: SERPINB5
Summary
InnateDB Gene IDBG-4411.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPINB5
Gene Name serpin peptidase inhibitor, clade B (ovalbumin), member 5
Synonyms maspin; PI5
Species Homo sapiens
Ensembl Gene ENSG00000206075
Encoded Proteins
IDBP-4413
serpin peptidase inhibitor, clade B (ovalbumin), member 5
IDBP-371866
serpin peptidase inhibitor, clade B (ovalbumin), member 5
IDBP-725998
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:63476761-63505085
Strand Forward strand
Band q21.33
Transcripts
ENST00000382771 ENSP00000372221
ENST00000424602 ENSP00000408821
ENST00000489441 ENSP00000467158
ENST00000465652
ENST00000464346
ENST00000588986
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 17 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0002009 morphogenesis of an epithelium
GO:0006928 cellular component movement
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
GO:0030198 extracellular matrix organization
GO:0050678 regulation of epithelial cell proliferation
GO:0060512 prostate gland morphogenesis
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000067006
View Gene Order
ENSBTAG00000002019
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04115
p53 signaling pathway pathway
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
atf2_pathway
ATF-2 transcription factor network
tap63pathway
Validated transcriptional targets of TAp63 isoforms
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.607460 Hs.622094
RefSeq NM_002639 XM_006722483
HUGO
OMIM
CCDS CCDS32839
HPRD 01111
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca