Version 5.4
Homo sapiens Gene: SEC11C
Summary
InnateDB Gene IDBG-4014.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEC11C
Gene Name SEC11 homolog C (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166562
Encoded Proteins
IDBP-4016
SEC11 homolog C (S. cerevisiae)
IDBP-810536
SEC11 homolog C (S. cerevisiae)
IDBP-727508
IDBP-727017
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 18:59139477-59158836
Strand Forward strand
Band q21.32
Transcripts
ENST00000299714 ENSP00000299714
ENST00000509791 ENSP00000482872
ENST00000588875 ENSP00000465281
ENST00000587834 ENSP00000468633
ENST00000591406
ENST00000592774
ENST00000593132
ENST00000585864
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006412 translation
GO:0006465 signal peptide processing
GO:0006508 proteolysis
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0044267 cellular protein metabolic process
GO:0050796 regulation of insulin secretion
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024516
View Gene Order
ENSBTAG00000011954
Not yet available
Pathways
NETPATH
REACTOME
REACT_19189
Synthesis, secretion, and deacylation of Ghrelin pathway
REACT_23824
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) pathway
REACT_24019
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) pathway
REACT_115902
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_1014
Translation pathway
REACT_23974
Incretin synthesis, secretion, and inactivation pathway
REACT_17015
Metabolism of proteins pathway
REACT_160078
Peptide hormone metabolism pathway
REACT_71
Gene Expression pathway
KEGG
hsa03060
Protein export pathway
INOH
PID NCI
Cross-References
SwissProt Q9BY50
TrEMBL B4DI03
UniProt Splice Variant
Entrez Gene 90701
UniGene Hs.45107 Hs.690840
RefSeq NM_033280 XM_005266779
HUGO HGNC:23400
OMIM
CCDS CCDS11970
HPRD 15310
IMGT
EMBL AF212233 AK295346 AK314107 BC009703 CH471096
GenPept AAH09703 AAK14919 BAG36800 BAG58315 EAW63089 EAW63090
RNA Seq Atlas 90701

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca