Version 5.4
Homo sapiens Gene: THOC5
Summary
InnateDB Gene IDBG-3643.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol THOC5
Gene Name THO complex 5
Synonyms C22orf19; Fmip; fSAP79; PK1.3
Species Homo sapiens
Ensembl Gene ENSG00000100296
Encoded Proteins
IDBP-592349
THO complex 5
IDBP-234344
THO complex 5
IDBP-234346
THO complex 5
IDBP-234348
THO complex 5
IDBP-370828
THO complex 5
IDBP-370842
THO complex 5
IDBP-370846
THO complex 5
IDBP-370848
THO complex 5
IDBP-370852
THO complex 5
IDBP-370854
THO complex 5
IDBP-370857
THO complex 5
IDBP-477137
THO complex 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 22:29505879-29555216
Strand Reverse strand
Band q12.2
Transcripts
ENST00000358079 ENSP00000444493
ENST00000397873 ENSP00000380971
ENST00000397872 ENSP00000380970
ENST00000397871 ENSP00000380969
ENST00000442555 ENSP00000416500
ENST00000443089 ENSP00000393247
ENST00000440771 ENSP00000413505
ENST00000455450 ENSP00000415425
ENST00000428374 ENSP00000416804
ENST00000414902 ENSP00000393420
ENST00000418021 ENSP00000388039
ENST00000490103 ENSP00000420306
ENST00000472164
ENST00000484924
ENST00000492707
ENST00000488052
ENST00000475187
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 51 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 51 [view]
Protein-Protein 51 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005515 protein binding
Biological Process
GO:0000902 cell morphogenesis
GO:0001824 blastocyst development
GO:0006397 mRNA processing
GO:0006406 mRNA export from nucleus
GO:0008380 RNA splicing
GO:0010468 regulation of gene expression
GO:0010793 regulation of mRNA export from nucleus
GO:0017145 stem cell division
GO:0030224 monocyte differentiation
GO:0032786 positive regulation of DNA-templated transcription, elongation
GO:0045650 negative regulation of macrophage differentiation
GO:0046784 intronless viral mRNA export from host nucleus
GO:0060215 primitive hemopoiesis
GO:2000002 negative regulation of DNA damage checkpoint
GO:2000035 regulation of stem cell division
Cellular Component
GO:0000346 transcription export complex
GO:0000347 THO complex
GO:0000445 THO complex part of transcription export complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016607 nuclear speck
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034274
View Gene Order
ENSBTAG00000013150
Not yet available
Pathways
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL C9JCL9 C9JXG5 C9JXU6 F8WCP5
UniProt Splice Variant
Entrez Gene 8563
UniGene Hs.75361
RefSeq NM_001002877 NM_001002878 NM_001002879 NM_003678 XM_005261801
HUGO HGNC:19074
OMIM 612733
CCDS CCDS13859
HPRD 16650
IMGT
EMBL AC005529
GenPept
RNA Seq Atlas 8563

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca