InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: MOCOS

Summary

InnateDB Gene

IDBG-2601.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MOCOS

Gene Name

molybdenum cofactor sulfurase

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000075643

Encoded Proteins

IDBP-2603

molybdenum cofactor sulfurase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

MOCOS sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH; MIM 607633) and aldehyde oxidase (AOX1; MIM 602841), which is required for their enzymatic activities (Ichida et al., 2001 [PubMed 11302742]).[supplied by OMIM, Feb 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 18:36187519-36272157

Strand

Forward strand

Band

q12.2

Transcripts

ENST00000261326	ENSP00000261326
ENST00000588132

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0008265	Mo-molybdopterin cofactor sulfurase activity
GO:0016740	transferase activity
GO:0016829	lyase activity
GO:0030151	molybdenum ion binding
GO:0030170	pyridoxal phosphate binding

Biological Process

GO:0006766	vitamin metabolic process
GO:0006767	water-soluble vitamin metabolic process
GO:0006777	Mo-molybdopterin cofactor biosynthetic process
GO:0008152	metabolic process
GO:0032324	molybdopterin cofactor biosynthetic process
GO:0043545	molybdopterin cofactor metabolic process
GO:0044281	small molecule metabolic process