Homo sapiens Gene: SLC4A7 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-22923.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | SLC4A7 | ||||||||||||||||||||||
Gene Name | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | ||||||||||||||||||||||
Synonyms | NBC2; NBC3; NBCN1; SBC2; SLC4A6 | ||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||
Ensembl Gene | ENSG00000033867 | ||||||||||||||||||||||
Encoded Proteins |
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 3:27372721-27484420 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | p24.1 | ||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||
Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Bicarbonate transporters pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Hs.250072 Hs.606925 Hs.623004 | ||||||||||||||||||||||
RefSeq | NM_001258379 NM_001258380 NM_003615 XM_005265598 XM_005265599 XM_005265600 XM_005265601 XM_006713421 | ||||||||||||||||||||||
HUGO | |||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS33721 CCDS58819 CCDS58820 | ||||||||||||||||||||||
HPRD | 04521 | ||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||