Version 5.4
Homo sapiens Gene: NEK10
Summary
InnateDB Gene IDBG-22793.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEK10
Gene Name NIMA-related kinase 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000163491
Encoded Proteins
IDBP-22795
NIMA (never in mitosis gene a)- related kinase 10
IDBP-22797
NIMA (never in mitosis gene a)- related kinase 10
IDBP-22799
NIMA (never in mitosis gene a)- related kinase 10
IDBP-22803
NIMA (never in mitosis gene a)- related kinase 10
IDBP-368458
NIMA (never in mitosis gene a)- related kinase 10
IDBP-368459
NIMA (never in mitosis gene a)- related kinase 10
IDBP-368465
NIMA (never in mitosis gene a)- related kinase 10
IDBP-368466
NIMA (never in mitosis gene a)- related kinase 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:27110085-27369460
Strand Reverse strand
Band p24.1
Transcripts
ENST00000295720 ENSP00000295720
ENST00000383771 ENSP00000373281
ENST00000383770 ENSP00000373280
ENST00000341435 ENSP00000343847
ENST00000424275 ENSP00000392344
ENST00000435584 ENSP00000412651
ENST00000435750 ENSP00000395338
ENST00000429845 ENSP00000395849
ENST00000498182
ENST00000460447
ENST00000474938
ENST00000491627
ENST00000574215
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005488 binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0031954 positive regulation of protein autophosphorylation
GO:0043406 positive regulation of MAP kinase activity
GO:0070372 regulation of ERK1 and ERK2 cascade
GO:1902749 regulation of cell cycle G2/M phase transition
Cellular Component
GO:1902911 protein kinase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042567
View Gene Order
ENSBTAG00000000220
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.427926 Hs.506115 Hs.721152 Hs.743887
RefSeq NM_199347 XM_006712994 XM_006712995 XM_006712996 XM_006712998 XM_006713002
HUGO
OMIM
CCDS CCDS46781
HPRD 08135
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca