InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: RAB5A

Summary

InnateDB Gene

IDBG-21702.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAB5A

Gene Name

RAB5A, member RAS oncogene family

Synonyms

RAB5

Species

Homo sapiens

Ensembl Gene

ENSG00000144566

Encoded Proteins

IDBP-21704

RAB5A, member RAS oncogene family

IDBP-367222

RAB5A, member RAS oncogene family

IDBP-367230

RAB5A, member RAS oncogene family

IDBP-367233

RAB5A, member RAS oncogene family

IDBP-367236

RAB5A, member RAS oncogene family

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:19947079-19985175

Strand

Forward strand

Band

p24.3

Transcripts

ENST00000273047	ENSP00000273047
ENST00000443878	ENSP00000398450
ENST00000412966	ENSP00000403533
ENST00000446547	ENSP00000396632
ENST00000422242	ENSP00000411941
ENST00000476544
ENST00000469122
ENST00000473608

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 86 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	86 [view]
Protein-Protein	86 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019001	guanyl nucleotide binding
GO:0019003	GDP binding
GO:0051021	GDP-dissociation inhibitor binding

Biological Process

GO:0006184	GTP catabolic process
GO:0006886	intracellular protein transport
GO:0006897	endocytosis
GO:0006913	nucleocytoplasmic transport
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0007399	nervous system development
GO:0007596	blood coagulation
GO:0014911	positive regulation of smooth muscle cell migration
GO:0015031	protein transport
GO:0030154	cell differentiation
GO:0045921	positive regulation of exocytosis
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0051489	regulation of filopodium assembly
GO:2000286	receptor internalization involved in canonical Wnt receptor signaling pathway

Cellular Component

GO:0001726	ruffle
GO:0005622	intracellular
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005768	endosome
GO:0005769	early endosome
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0008021	synaptic vesicle
GO:0010008	endosome membrane
GO:0015629	actin cytoskeleton
GO:0016020	membrane
GO:0030139	endocytic vesicle
GO:0030424	axon
GO:0030425	dendrite
GO:0031901	early endosome membrane
GO:0042470	melanosome
GO:0042589	zymogen granule membrane
GO:0043005	neuron projection
GO:0043025	neuronal cell body
GO:0043195	terminal bouton
GO:0043234	protein complex
GO:0045121	membrane raft
GO:0045335	phagocytic vesicle
GO:0048471	perinuclear region of cytoplasm
GO:0055037	recycling endosome
GO:0070062	extracellular vesicular exosome