Homo sapiens Gene: DSG4 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||
InnateDB Gene | IDBG-2037.5 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | DSG4 | ||||||||||||
Gene Name | desmoglein 4 | ||||||||||||
Synonyms | |||||||||||||
Species | Homo sapiens | ||||||||||||
Ensembl Gene | ENSG00000175065 | ||||||||||||
Encoded Proteins |
desmoglein 4
desmoglein 4
|
||||||||||||
Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
Entrez Gene | |||||||||||||
Summary |
This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded protein is a transmembrane component in desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and potentially in other skin disorders. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] |
||||||||||||
Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 18:31376777-31414912 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | q12.1 | ||||||||||||
Transcripts |
|
||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||||||||
Gene Ontology | |||||||||||||
Molecular Function |
|
||||||||||||
Biological Process |
|
||||||||||||
Cellular Component |
|
||||||||||||
Orthologs | |||||||||||||
Species
Mus musculus
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||
Cross-References | |||||||||||||
SwissProt | Q86SJ6 | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 147409 | ||||||||||||
UniGene | Hs.407618 | ||||||||||||
RefSeq | NM_001134453 NM_177986 | ||||||||||||
HUGO | HGNC:21307 | ||||||||||||
OMIM | 607892 | ||||||||||||
CCDS | CCDS11897 CCDS45845 | ||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | AY168788 AY177663 AY177664 AY227350 AY228236 BC039098 BC132907 BC132909 | ||||||||||||
GenPept | AAH39098 AAI32908 AAI32910 AAO43657 AAO47077 AAO47078 AAP45000 AAP49811 | ||||||||||||
RNA Seq Atlas | 147409 | ||||||||||||