Version 5.4
Homo sapiens Gene: MYO9A
Summary
InnateDB Gene IDBG-19982.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYO9A
Gene Name myosin IXA
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000066933
Encoded Proteins
IDBP-19984
myosin IXA
IDBP-376718
myosin IXA
IDBP-376721
myosin IXA
IDBP-747480
IDBP-747201
IDBP-744831
IDBP-745130
IDBP-744735
IDBP-746957
IDBP-747783
IDBP-746368
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with Bardet-Biedl Syndrome. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:71822289-72118577
Strand Reverse strand
Band q23
Transcripts
ENST00000356056 ENSP00000348349
ENST00000424560 ENSP00000399162
ENST00000444904 ENSP00000398250
ENST00000566744
ENST00000564571 ENSP00000456192
ENST00000563925
ENST00000568042 ENSP00000457407
ENST00000563648
ENST00000567560
ENST00000564699
ENST00000563071
ENST00000567095
ENST00000561618 ENSP00000457945
ENST00000565528
ENST00000568438 ENSP00000457235
ENST00000563542
ENST00000568481 ENSP00000455150
ENST00000569314 ENSP00000454517
ENST00000566885 ENSP00000454446
ENST00000568781
ENST00000564931 ENSP00000456882
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0003779 actin binding
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0007601 visual perception
GO:0008152 metabolic process
GO:0035556 intracellular signal transduction
GO:0043547 positive regulation of GTPase activity
GO:0051056 regulation of small GTPase mediated signal transduction
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0016021 integral component of membrane
GO:0016459 myosin complex
GO:0016461 unconventional myosin complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039585
View Gene Order
ENSBTAG00000007433
Not yet available
Pathways
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.513000 Hs.546268 Hs.603904 Hs.710218 Hs.733087
RefSeq NM_006901
HUGO
OMIM
CCDS CCDS10239
HPRD 05341
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca