Version 5.4
Homo sapiens Gene: BAZ1B
Summary
InnateDB Gene IDBG-19888.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BAZ1B
Gene Name bromodomain adjacent to zinc finger domain, 1B
Synonyms WBSCR10; WBSCR9; WSTF
Species Homo sapiens
Ensembl Gene ENSG00000009954
Encoded Proteins
IDBP-19890
bromodomain adjacent to zinc finger domain, 1B
IDBP-293167
bromodomain adjacent to zinc finger domain, 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:73440398-73522278
Strand Reverse strand
Band q11.23
Transcripts
ENST00000339594 ENSP00000342434
ENST00000404251 ENSP00000385442
ENST00000466844
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 66 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 66 [view]
Protein-Protein 60 [view]
Protein-DNA 6 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0004713 protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005488 binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0035173 histone kinase activity
GO:0042393 histone binding
GO:0070577 lysine-acetylated histone binding
GO:0071884 vitamin D receptor activator activity
Biological Process
GO:0003007 heart morphogenesis
GO:0006302 double-strand break repair
GO:0006333 chromatin assembly or disassembly
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006974 cellular response to DNA damage stimulus
GO:0016572 histone phosphorylation
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0048096 chromatin-mediated maintenance of transcription
Cellular Component
GO:0000793 condensed chromosome
GO:0005634 nucleus
GO:0005721 centromeric heterochromatin
GO:0043596 nuclear replication fork
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000002748
View Gene Order
ENSBTAG00000005197
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9UIG0
TrEMBL
UniProt Splice Variant
Entrez Gene 9031
UniGene Hs.743372
RefSeq NM_032408 XM_005250683
HUGO HGNC:961
OMIM 605681
CCDS CCDS5549
HPRD
IMGT
EMBL AB032253 AC005074 AC005089 AF072810 AF084479 BC065029 BC136520 CH471200
GenPept AAC97879 AAD04720 AAD08675 AAH65029 AAI36521 AAP22332 BAA89210 EAW69680 EAW69681
RNA Seq Atlas 9031

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca