Version 5.4
Homo sapiens Gene: AAGAB
Summary
InnateDB Gene IDBG-18472.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AAGAB
Gene Name alpha- and gamma-adaptin binding protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000103591
Encoded Proteins
IDBP-18474
alpha- and gamma-adaptin binding protein
IDBP-601945
alpha- and gamma-adaptin binding protein
IDBP-591828
alpha- and gamma-adaptin binding protein
IDBP-602536
alpha- and gamma-adaptin binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:67201033-67255195
Strand Reverse strand
Band q23
Transcripts
ENST00000261880 ENSP00000261880
ENST00000538028
ENST00000561452 ENSP00000453263
ENST00000542650 ENSP00000440735
ENST00000558725
ENST00000560362 ENSP00000453059
ENST00000561229
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037257
View Gene Order
ENSBTAG00000040368
Not yet available
Cross-References
SwissProt
TrEMBL H0YL49 Q5JPJ4
UniProt Splice Variant
Entrez Gene 79719
UniGene Hs.596292
RefSeq NM_001271886 NM_001271885 NM_024666
HUGO HGNC:25662
OMIM 614888
CCDS CCDS61679 CCDS42050
HPRD 07754
IMGT
EMBL AC012568 AC110292 AL832256
GenPept CAI46180
RNA Seq Atlas 79719

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca