Version 5.4
Homo sapiens Gene: GCFC1
Summary
InnateDB Gene IDBG-1817.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GCFC1
Gene Name GC-rich sequence DNA-binding factor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000159086
Encoded Proteins
IDBP-1821
GC-rich sequence DNA-binding factor 1
IDBP-1825
GC-rich sequence DNA-binding factor 1
IDBP-362481
GC-rich sequence DNA-binding factor 1
IDBP-362483
GC-rich sequence DNA-binding factor 1
IDBP-362491
GC-rich sequence DNA-binding factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that may bind to GC-rich DNA sequences, which suggests its involvement in the regulation of transcription. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:32733899-32771858
Strand Reverse strand
Band q22.11
Transcripts
ENST00000331923 ENSP00000328992
ENST00000290178 ENSP00000290178
ENST00000443785 ENSP00000393038
ENST00000445049 ENSP00000408048
ENST00000421049 ENSP00000388973
ENST00000466846
ENST00000497873
ENST00000472588
ENST00000464256
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0008134 transcription factor binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007517 muscle organ development
GO:0014842 regulation of satellite cell proliferation
GO:0031062 positive regulation of histone methylation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:2000288 positive regulation of myoblast proliferation
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022974
View Gene Order
ENSBTAG00000003064
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.644004 Hs.719479
RefSeq NM_013329 NM_016631 XM_006724067
HUGO
OMIM
CCDS CCDS13619 CCDS33541
HPRD 10761
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca