Version 5.4
Homo sapiens Gene: PTPLAD1
Summary
InnateDB Gene IDBG-17546.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTPLAD1
Gene Name protein tyrosine phosphatase-like A domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000074696
Encoded Proteins
IDBP-17548
protein tyrosine phosphatase-like A domain containing 1
IDBP-375428
protein tyrosine phosphatase-like A domain containing 1
IDBP-747565
IDBP-746885
IDBP-745733
IDBP-744942
IDBP-746355
IDBP-747400
IDBP-744987
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 15:65530418-65578352
Strand Forward strand
Band q22.31
Transcripts
ENST00000261875 ENSP00000261875
ENST00000442729 ENSP00000392491
ENST00000566074 ENSP00000456300
ENST00000566511 ENSP00000455587
ENST00000566239
ENST00000562901 ENSP00000455686
ENST00000568793 ENSP00000455530
ENST00000565299 ENSP00000456568
ENST00000561763
ENST00000562832 ENSP00000454610
ENST00000569894 ENSP00000454873
ENST00000624437
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
Experimentally validated
Total 34 [view]
Protein-Protein 33 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0016829 lyase activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0007254 JNK cascade
GO:0007257 activation of JUN kinase activity
GO:0007264 small GTPase mediated signal transduction
GO:0007266 Rho protein signal transduction
GO:0016601 Rac protein signal transduction
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005575 cellular_component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033629
View Gene Order
ENSBTAG00000015155
Not yet available
Cross-References
SwissProt
TrEMBL B4DRF4
UniProt Splice Variant
Entrez Gene 51495
UniGene Hs.512973 Hs.710476 Hs.713694 Hs.714081
RefSeq NM_016395
HUGO HGNC:24175
OMIM 615940
CCDS CCDS45282
HPRD 11037
IMGT
EMBL AC011846 AC027220 AK299234
GenPept BAG61266
RNA Seq Atlas 51495

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca