Version 5.4
Homo sapiens Gene: FIGNL1
Summary
InnateDB Gene IDBG-16569.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FIGNL1
Gene Name fidgetin-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132436
Encoded Proteins
IDBP-16571
fidgetin-like 1
IDBP-239316
fidgetin-like 1
IDBP-375220
fidgetin-like 1
IDBP-375222
fidgetin-like 1
IDBP-375226
fidgetin-like 1
IDBP-375230
fidgetin-like 1
IDBP-375232
fidgetin-like 1
IDBP-375233
fidgetin-like 1
IDBP-375236
fidgetin-like 1
IDBP-375238
fidgetin-like 1
IDBP-808270
fidgetin-like 1
IDBP-808271
fidgetin-like 1
IDBP-808273
fidgetin-like 1
IDBP-808274
fidgetin-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:50444128-50542535
Strand Reverse strand
Band p12.1
Transcripts
ENST00000356889 ENSP00000349356
ENST00000395556 ENSP00000378924
ENST00000433017 ENSP00000399997
ENST00000419119 ENSP00000410811
ENST00000435566 ENSP00000409674
ENST00000436590 ENSP00000394070
ENST00000422854 ENSP00000403012
ENST00000440350 ENSP00000388471
ENST00000420829 ENSP00000409281
ENST00000448788 ENSP00000402957
ENST00000617389 ENSP00000483126
ENST00000615084 ENSP00000483543
ENST00000611938 ENSP00000484551
ENST00000613602 ENSP00000481751
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0017111 nucleoside-triphosphatase activity
Biological Process
GO:0001649 osteoblast differentiation
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0010569 regulation of double-strand break repair via homologous recombination
GO:0033687 osteoblast proliferation
GO:0043066 negative regulation of apoptotic process
GO:0046034 ATP metabolic process
GO:0051726 regulation of cell cycle
GO:0071479 cellular response to ionizing radiation
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway
Cellular Component
GO:0000228 nuclear chromosome
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035455
View Gene Order
ENSBTAG00000001500
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.137516 Hs.701912
RefSeq NM_001042762 NM_001287492 NM_001287493 NM_001287494 NM_001287495 NM_001287496 NM_022116 XM_005271783
HUGO
OMIM
CCDS CCDS5510
HPRD 10958
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca