Version 5.4
Homo sapiens Gene: VWC2
Summary
InnateDB Gene IDBG-16321.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VWC2
Gene Name von Willebrand factor C domain containing 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000188730
Encoded Proteins
IDBP-16323
von Willebrand factor C domain containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a secreted bone morphogenic protein antagonist. The encoded protein is possibly involved in neural function and development and may have a role in cell adhesion.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:49773661-49921950
Strand Forward strand
Band p12.2
Transcripts
ENST00000340652 ENSP00000341819
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0010811 positive regulation of cell-substrate adhesion
GO:0030514 negative regulation of BMP signaling pathway
GO:0045666 positive regulation of neuron differentiation
Cellular Component
GO:0005604 basement membrane
GO:0005614 interstitial matrix
GO:0005615 extracellular space
GO:0030054 cell junction
GO:0031012 extracellular matrix
GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0045202 synapse
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000050830
View Gene Order
ENSBTAG00000044068
Not yet available
Cross-References
SwissProt Q2TAL6
TrEMBL
UniProt Splice Variant
Entrez Gene 375567
UniGene Hs.629302
RefSeq NM_198570
HUGO HGNC:30200
OMIM 611108
CCDS CCDS5508
HPRD
IMGT
EMBL AB292671 AY358393 BC110857 CH236955 CH471128
GenPept AAI10858 AAQ88759 BAF51551 EAL23904 EAW60985
RNA Seq Atlas 375567

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca