Version 5.4
Homo sapiens Gene: ZDHHC8
Summary
InnateDB Gene IDBG-1624.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZDHHC8
Gene Name zinc finger, DHHC-type containing 8
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000099904
Encoded Proteins
IDBP-1626
zinc finger, DHHC-type containing 8
IDBP-1628
zinc finger, DHHC-type containing 8
IDBP-292561
zinc finger, DHHC-type containing 8
IDBP-362827
zinc finger, DHHC-type containing 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:20129456-20148007
Strand Forward strand
Band q11.21
Transcripts
ENST00000320602 ENSP00000317804
ENST00000334554 ENSP00000334490
ENST00000405930 ENSP00000384716
ENST00000436518 ENSP00000412807
ENST00000468112
ENST00000469212
ENST00000472497
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016409 palmitoyltransferase activity
GO:0019706 protein-cysteine S-palmitoyltransferase activity
Biological Process
GO:0007275 multicellular organismal development
GO:0007626 locomotory behavior
GO:0008152 metabolic process
GO:0018345 protein palmitoylation
Cellular Component
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030659 cytoplasmic vesicle membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000060166
View Gene Order
ENSBTAG00000006657
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.625140 Hs.63128
RefSeq NM_001185024 NM_013373 XM_006724239
HUGO
OMIM
CCDS CCDS13776 CCDS54502
HPRD 12298
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca