InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: ENO2

Summary

InnateDB Gene

IDBG-15559.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ENO2

Gene Name

enolase 2 (gamma, neuronal)

Synonyms

HEL-S-279; NSE

Species

Homo sapiens

Ensembl Gene

ENSG00000111674

Encoded Proteins

IDBP-15561

enolase 2 (gamma, neuronal)

IDBP-598357

enolase 2 (gamma, neuronal)

IDBP-586063

enolase 2 (gamma, neuronal)

IDBP-603424

enolase 2 (gamma, neuronal)

IDBP-601441

enolase 2 (gamma, neuronal)

IDBP-590160

enolase 2 (gamma, neuronal)

IDBP-807419

enolase 2 (gamma, neuronal)

IDBP-807420

enolase 2 (gamma, neuronal)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:6913745-6923698

Strand

Forward strand

Band

p13.31

Transcripts

ENST00000229277	ENSP00000229277
ENST00000441285
ENST00000537688	ENSP00000445788
ENST00000541477	ENSP00000438873
ENST00000537838
ENST00000536199
ENST00000538763	ENSP00000441490
ENST00000539713
ENST00000542509
ENST00000535366	ENSP00000437402
ENST00000545045	ENSP00000438062
ENST00000535275	ENSP00000476096
ENST00000543975	ENSP00000476112
ENST00000534977

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.

Experimentally validated
Total	49 [view]
Protein-Protein	45 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004634	phosphopyruvate hydratase activity

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006006	glucose metabolic process
GO:0006094	gluconeogenesis
GO:0006096	glycolytic process
GO:0044281	small molecule metabolic process

Cellular Component

GO:0000015	phosphopyruvate hydratase complex
GO:0001917	photoreceptor inner segment
GO:0005615	extracellular space
GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0043025	neuronal cell body
GO:0043204	perikaryon
GO:0070062	extracellular vesicular exosome