Version 5.4
Homo sapiens Gene: TRIP13
Summary
InnateDB Gene IDBG-10685.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIP13
Gene Name thyroid hormone receptor interactor 13
Synonyms 16E1BP
Species Homo sapiens
Ensembl Gene ENSG00000071539
Encoded Proteins
IDBP-10689
thyroid hormone receptor interactor 13
IDBP-475815
thyroid hormone receptor interactor 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:892643-919357
Strand Forward strand
Band p15.33
Transcripts
ENST00000166345 ENSP00000166345
ENST00000512024
ENST00000508456
ENST00000513435 ENSP00000427528
ENST00000510412
ENST00000509210
ENST00000508430
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 90 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 90 [view]
Protein-Protein 87 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003712 transcription cofactor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0017111 nucleoside-triphosphatase activity
GO:0042802 identical protein binding
Biological Process
GO:0001556 oocyte maturation
GO:0006302 double-strand break repair
GO:0006366 transcription from RNA polymerase II promoter
GO:0007130 synaptonemal complex assembly
GO:0007131 reciprocal meiotic recombination
GO:0007141 male meiosis I
GO:0007144 female meiosis I
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0048477 oogenesis
GO:2001141 regulation of RNA biosynthetic process
Cellular Component
GO:0001673 male germ cell nucleus
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021569
View Gene Order
ENSBTAG00000006972
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.731712 Hs.734471
RefSeq NM_004237
HUGO
OMIM
CCDS CCDS3858
HPRD 05145
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca