Mus musculus Gene: Ccl28
Summary
InnateDB Gene IDBG-705098.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ccl28
Gene Name chemokine (C-C motif) ligand 28
Synonyms CCK1; MEC; Scya28
Species Mus musculus
Ensembl Gene ENSMUSG00000074715
Encoded Proteins
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151882:
This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for resting CD4 or CD8 T cells and eosinophils. The product of this gene binds to chemokine receptors CCR3 and CCR10. This chemokine may play a role in the physiology of extracutaneous epithelial tissues, including diverse mucosal organs. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:119623819-119654354
Strand Forward strand
Band D2.3
Transcripts
ENSMUST00000099241 ENSMUSP00000096847
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008009 chemokine activity
Biological Process
GO:0006955 immune response
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007584 response to nutrient
GO:0060326 cell chemotaxis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (i) signalling events pathway
Chemokine receptors bind chemokines pathway
Signal Transduction pathway
KEGG
Cytokine-cytokine receptor interaction pathway
Chemokine signaling pathway pathway
Intestinal immune network for IgA production pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (i) signalling events pathway
Chemokine receptors bind chemokines pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
Cytokine-cytokine receptor interaction pathway
Chemokine signaling pathway pathway
Intestinal immune network for IgA production pathway
INOH
PID NCI
Cross-References
SwissProt Q9JIL2
TrEMBL
UniProt Splice Variant
Entrez Gene 56838
UniGene Mm.143745
RefSeq NM_020279
OMIM
CCDS CCDS56900
HPRD
IMGT
MGI ID MGI:1861731
MGI Symbol Ccl28
EMBL AF220238 BC055864
GenPept AAF87206 AAH55864
RNA Seq Atlas 56838