Version 5.4
Bos taurus Gene: BT.105478
Summary
InnateDB Gene IDBG-646662.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.105478
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011831
Encoded Proteins
IDBP-699486
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138600:
This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:59779604-59813156
Strand Forward strand
Band
Transcripts
ENSBTAT00000015701 ENSBTAP00000015701
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004190 aspartic-type endopeptidase activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006509 membrane protein ectodomain proteolysis
GO:0031293 membrane protein intracellular domain proteolysis
GO:0050776 regulation of immune response
Cellular Component
GO:0005765 lysosomal membrane
GO:0016021 integral component of membrane
GO:0030660 Golgi-associated vesicle membrane
GO:0031902 late endosome membrane
GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000138600
View Gene Order
ENSMUSG00000027366
View Gene Order
Cross-References
SwissProt
TrEMBL F1MG08
UniProt Splice Variant
Entrez Gene 530325
UniGene Bt.105478
RefSeq XM_002690970 XM_608794
HUGO HGNC:30227
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02029064 DAAA02029065
GenPept
RNA Seq Atlas 530325

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca