Version 5.4
Bos taurus Gene: LSP1
Summary
InnateDB Gene IDBG-645275.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LSP1
Gene Name lymphocyte-specific protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010447
Encoded Proteins
IDBP-697973
lymphocyte-specific protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130592:
This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:50238211-50276209
Strand Reverse strand
Band
Transcripts
ENSBTAT00000013787 ENSBTAP00000013787
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
Biological Process
GO:0006935 chemotaxis
GO:0006952 defense response
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000130592
View Gene Order
ENSMUSG00000018819
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
p38_mk2pathway
p38 signaling mediated by MAPKAP kinases
Cross-References
SwissProt
TrEMBL Q0P5E0
UniProt Splice Variant
Entrez Gene 508832
UniGene Bt.7220
RefSeq NM_001075374 XM_005227324 XM_005227325 XM_005227326 XM_005227327
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120173 DAAA02063738
GenPept AAI20174
RNA Seq Atlas 508832

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca