Bos taurus Gene: CEP135
Summary
InnateDB Gene IDBG-642457.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CEP135
Gene Name centrosomal protein of 135 kDa
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009471
Encoded Proteins
CEP135 proteinUncharacterized protein
CEP135 proteinUncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174799:
This gene encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in this gene are associated with autosomal recessive primary microcephaly-8. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:73021614-73095955
Strand Forward strand
Band
Transcripts
ENSBTAT00000012468 ENSBTAP00000012468
ENSBTAT00000046289 ENSBTAP00000043603
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0008022 protein C-terminus binding
Biological Process
GO:0007099 centriole replication
GO:0010457 centriole-centriole cohesion
Cellular Component
GO:0005813 centrosome
GO:0005814 centriole
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Regulation of PLK1 Activity at G2/M Transition pathway
Loss of Nlp from mitotic centrosomes pathway
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Cell Cycle pathway
Centrosome maturation pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
Recruitment of mitotic centrosome proteins and complexes pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Loss of Nlp from mitotic centrosomes pathway
Cell Cycle pathway
Mitotic G2-G2/M phases pathway
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
Regulation of PLK1 Activity at G2/M Transition pathway
Centrosome maturation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1ME99 Q32KW4
UniProt Splice Variant
Entrez Gene 509483
UniGene Bt.43589
RefSeq NM_001075406
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109893 DAAA02017737 DAAA02017738
GenPept AAI09894
RNA Seq Atlas 509483