Version 5.4
Bos taurus Gene: INTS1
Summary
InnateDB Gene IDBG-641372.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INTS1
Gene Name integrator complex subunit 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000642
Encoded Proteins
IDBP-693774
integrator complex subunit 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164880:
INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:41983696-42007511
Strand Forward strand
Band
Transcripts
ENSBTAT00000000845 ENSBTAP00000000845
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
Biological Process
GO:0001832 blastocyst growth
GO:0001833 inner cell mass cell proliferation
GO:0016180 snRNA processing
GO:0034474 U2 snRNA 3'-end processing
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
GO:0032039 integrator complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000164880
View Gene Order
ENSMUSG00000029547
View Gene Order
Cross-References
SwissProt
TrEMBL E1B8S1
UniProt Splice Variant
Entrez Gene 790146
UniGene Bt.64674
RefSeq NM_001191470 XM_005225250
HUGO HGNC:24555
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02058406
GenPept
RNA Seq Atlas 790146

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca