Version 5.4
Bos taurus Gene: SATB1
Summary
InnateDB Gene IDBG-640809.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SATB1
Gene Name DNA-binding protein SATB1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021158
Encoded Proteins
IDBP-693114
DNA-binding protein SATB1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182568:
This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:157169740-157261755
Strand Reverse strand
Band
Transcripts
ENSBTAT00000028199 ENSBTAP00000028199
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008544 epidermis development
GO:0016571 histone methylation
GO:0042110 T cell activation
GO:0043367 CD4-positive, alpha-beta T cell differentiation
GO:0043374 CD8-positive, alpha-beta T cell differentiation
GO:0050798 activated T cell proliferation
GO:0060004 reflex
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005720 nuclear heterochromatin
GO:0016363 nuclear matrix
GO:0016605 PML body
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000182568
View Gene Order
ENSMUSG00000023927
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_107
Apoptotic cleavage of cellular proteins pathway
REACT_995
Apoptotic execution phase pathway
REACT_578
Apoptosis pathway
REACT_258521
Apoptosis pathway
REACT_224460
Apoptotic cleavage of cellular proteins pathway
REACT_207035
Apoptotic execution phase pathway
KEGG
INOH
PID NCI
caspase_pathway
Caspase Cascade in Apoptosis
Cross-References
SwissProt
TrEMBL A7MB41
UniProt Splice Variant
Entrez Gene 516952
UniGene Bt.44470
RefSeq NM_001102040 XM_005202140
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151323 DAAA02003773 DAAA02003774 DAAA02003775
GenPept AAI51324
RNA Seq Atlas 516952

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca