Version 5.4
Bos taurus Gene: FBXO25
Summary
InnateDB Gene IDBG-640428.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXO25
Gene Name F-box only protein 25
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007039
Encoded Proteins
IDBP-692692
F-box only protein 25
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147364:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:148266955-148295000
Strand Forward strand
Band
Transcripts
ENSBTAT00000009259 ENSBTAP00000009259
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 100 interaction(s) predicted by orthology.
Predicted by orthology
Total 100 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005634 nucleus
GO:0019005 SCF ubiquitin ligase complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000147364
View Gene Order
ENSMUSG00000038365
View Gene Order
Cross-References
SwissProt Q1RMS8
TrEMBL
UniProt Splice Variant
Entrez Gene 540328
UniGene Bt.1450
RefSeq NM_001076211 XM_005202090
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114733
GenPept AAI14734
RNA Seq Atlas 540328

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca