Version 5.4
| Bos taurus Gene: MAPK1 | |||||||||||||||||||||||||||||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||||||||||||||||||||||||||||
| InnateDB Gene | IDBG-637539.3 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||||||||||||||||||||||||||
| Gene Symbol | MAPK1 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Gene Name | Mitogen-activated protein kinase 1 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Synonyms | ERK2 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Species | Bos taurus | ||||||||||||||||||||||||||||||||||||||||||||||||
| Ensembl Gene | ENSBTAG00000010312 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Encoded Proteins |
Mitogen-activated protein kinase 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||||||||||||||||||||||||||
| InnateDB Annotation from Orthologs | |||||||||||||||||||||||||||||||||||||||||||||||||
| Summary |
[Homo sapiens] MAPK1 (ERK) and MAPK14 (p38) control the dynamic balance regulating neutrophil migration.
[Mus musculus] Mapk1 (ERK) and Mapk14 (p38) control the dynamic balance regulating neutrophil migration. (Demonstrated in human)
[Mus musculus] Ptpn11 phosphatase function positively regulates Clec7a- and Itgam-stimulated reactive oxygen species production in macrophages by dephosphorylating and thus mitigating the inhibitory function of Sirpa and by promoting Mapk1/Mapk3 activation.
[Mus musculus] Prostaglandin E2 transactivates Csf1r and synergizes with its signalling at Mapk1/Mapk3 level in promoting macrophage migration.
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| Entrez Gene | |||||||||||||||||||||||||||||||||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100030:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008] This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014] |
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| Gene Information | |||||||||||||||||||||||||||||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||||||||||||||||||||||||||||
| Genomic Location | Chromosome 17:74016493-74035118 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||||||||||||||||||||||||||||||||
| Band | |||||||||||||||||||||||||||||||||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||||||||||||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 198 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||||||||||||||||||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||||||||||||||||||||||||||||||||||||||||||
| NETPATH | |||||||||||||||||||||||||||||||||||||||||||||||||
| REACTOME |
DAP12 interactions pathway
Insulin receptor signalling cascade pathway
ERKs are inactivated pathway
Signaling by EGFR pathway
ARMS-mediated activation pathway
Signalling to ERKs pathway
Recycling pathway of L1 pathway
Toll Like Receptor 2 (TLR2) Cascade pathway
Negative regulation of FGFR signaling pathway
Regulation of HSF1-mediated heat shock response pathway
GRB2 events in ERBB2 signaling pathway
TRIF-mediated TLR3/TLR4 signaling pathway
Oncogene Induced Senescence pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
SOS-mediated signalling pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
IRS-related events triggered by IGF1R pathway
Toll Like Receptor 3 (TLR3) Cascade pathway
Post NMDA receptor activation events pathway
NCAM signaling for neurite out-growth pathway
ERK activation pathway
Signaling by GPCR pathway
Signaling by PDGF pathway
Activated TLR4 signalling pathway
Toll Like Receptor 7/8 (TLR7/8) Cascade pathway
M Phase pathway
MyD88-independent cascade pathway
Signaling by Leptin pathway
Signaling by ERBB4 pathway
SHC-mediated signalling pathway
Toll Like Receptor 9 (TLR9) Cascade pathway
L1CAM interactions pathway
MyD88:Mal cascade initiated on plasma membrane pathway
Toll Like Receptor 5 (TLR5) Cascade pathway
SHC1 events in ERBB2 signaling pathway
Signaling by FGFR pathway
Interleukin-2 signaling pathway
Cytokine Signaling in Immune system pathway
Prolonged ERK activation events pathway
Cellular responses to stress pathway
IRS-related events pathway
VEGFA-VEGFR2 Pathway pathway
RSK activation pathway
SHC1 events in EGFR signaling pathway
Hemostasis pathway
Immune System pathway
Cell Cycle, Mitotic pathway
IRS-mediated signalling pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
Transmission across Chemical Synapses pathway
Platelet activation, signaling and aggregation pathway
MAP kinase activation in TLR cascade pathway
IGF1R signaling cascade pathway
Signal transduction by L1 pathway
VEGFR2 mediated cell proliferation pathway
SHC-related events pathway
Signaling by ERBB2 pathway
Toll-Like Receptors Cascades pathway
Cell Cycle pathway
Signal Transduction pathway
Nuclear Events (kinase and transcription factor activation) pathway
Cellular Senescence pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events pathway
Signaling by Insulin receptor pathway
Signaling by EGFR in Cancer pathway
Signalling to RAS pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Golgi Cisternae Pericentriolar Stack Reorganization pathway
Regulation of actin dynamics for phagocytic cup formation pathway
RAF/MAP kinase cascade pathway
SHC1 events in ERBB4 signaling pathway
G-protein mediated events pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Axon guidance pathway
Toll Like Receptor 10 (TLR10) Cascade pathway
Signalling to p38 via RIT and RIN pathway
Oxidative Stress Induced Senescence pathway
SHC-related events triggered by IGF1R pathway
Toll Like Receptor TLR6:TLR2 Cascade pathway
Advanced glycosylation endproduct receptor signaling pathway
CREB phosphorylation through the activation of Ras pathway
NGF signalling via TRKA from the plasma membrane pathway
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation pathway
PLC beta mediated events pathway
Downstream signaling of activated FGFR pathway
Neuronal System pathway
phospho-PLA2 pathway pathway
Mitotic Prophase pathway
Signalling by NGF pathway
Signaling by VEGF pathway
Cellular response to heat stress pathway
ERK/MAPK targets pathway
Growth hormone receptor signaling pathway
GRB2 events in EGFR signaling pathway
Toll Like Receptor TLR1:TLR2 Cascade pathway
MyD88 dependent cascade initiated on endosome pathway
MAPK targets/ Nuclear events mediated by MAP kinases pathway
Downstream signal transduction pathway
Opioid Signalling pathway
Signaling by SCF-KIT pathway
Innate Immune System pathway
Senescence-Associated Secretory Phenotype (SASP) pathway
FCERI mediated MAPK activation pathway
Activation of the AP-1 family of transcription factors pathway
Ca-dependent events pathway
Frs2-mediated activation pathway
FRS2-mediated cascade pathway
Signaling by Interleukins pathway
DAP12 signaling pathway
Disease pathway
Signaling by FGFR in disease pathway
Toll Like Receptor 4 (TLR4) Cascade pathway
Fc epsilon receptor (FCERI) signaling pathway
MyD88 cascade initiated on plasma membrane pathway
Developmental Biology pathway
ERK2 activation pathway
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| KEGG | |||||||||||||||||||||||||||||||||||||||||||||||||
| INOH | |||||||||||||||||||||||||||||||||||||||||||||||||
| PID NCI | |||||||||||||||||||||||||||||||||||||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||||||||||||||||||||||||||
| NETPATH |
Alpha6Beta4Integrin pathway
Notch pathway
EGFR1 pathway
ID pathway
KitReceptor pathway
TGF_beta_Receptor pathway
Wnt pathway
TNFalpha pathway
TCR pathway
BCR pathway
IL1 pathway
IL2 pathway
IL3 pathway
IL4 pathway
IL5 pathway
IL6 pathway
IL-7 pathway
IL9 pathway
RANKL pathway
Leptin pathway
TSH pathway
TSLP pathway
FSH pathway
TWEAK pathway
Prolactin pathway
IL11 pathway
Oncostatin_M pathway
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| REACTOME |
Golgi Cisternae Pericentriolar Stack Reorganization pathway
ERK2 activation pathway
ERK activation pathway
DAP12 signaling pathway
DAP12 interactions pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Advanced glycosylation endproduct receptor signaling pathway
ERKs are inactivated pathway
ERK/MAPK targets pathway
Activation of the AP-1 family of transcription factors pathway
MyD88-independent cascade pathway
Toll Like Receptor 3 (TLR3) Cascade pathway
MyD88:Mal cascade initiated on plasma membrane pathway
Toll Like Receptor TLR1:TLR2 Cascade pathway
Toll Like Receptor TLR6:TLR2 Cascade pathway
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation pathway
MyD88 dependent cascade initiated on endosome pathway
Toll Like Receptor 9 (TLR9) Cascade pathway
MyD88 cascade initiated on plasma membrane pathway
Toll Like Receptor 10 (TLR10) Cascade pathway
Toll Like Receptor 4 (TLR4) Cascade pathway
Toll Like Receptor 5 (TLR5) Cascade pathway
Growth hormone receptor signaling pathway
Interleukin-2 signaling pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Frs2-mediated activation pathway
ARMS-mediated activation pathway
Signalling to p38 via RIT and RIN pathway
Signalling to RAS pathway
SOS-mediated signalling pathway
Signal attenuation pathway
SHC1 events in EGFR signaling pathway
GRB2 events in EGFR signaling pathway
Signaling by EGFR pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
phospho-PLA2 pathway pathway
PLC beta mediated events pathway
Opioid Signalling pathway
SHC1 events in ERBB4 signaling pathway
Signaling by ERBB4 pathway
SHC-mediated signalling pathway
Signaling by Insulin receptor pathway
IRS-related events triggered by IGF1R pathway
SHC-related events triggered by IGF1R pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
GRB2 events in ERBB2 signaling pathway
SHC1 events in ERBB2 signaling pathway
Signaling by ERBB2 pathway
Negative regulation of FGFR signaling pathway
FRS2-mediated cascade pathway
Signaling by FGFR pathway
Signaling by SCF-KIT pathway
Downstream signal transduction pathway
Signaling by PDGF pathway
RSK activation pathway
CREB phosphorylation through the activation of Ras pathway
Signal transduction by L1 pathway
Recycling pathway of L1 pathway
L1CAM interactions pathway
NCAM signaling for neurite out-growth pathway
Signaling by FGFR in disease pathway
SHC-related events pathway
Cellular responses to stress pathway
Developmental Biology pathway
Oncogene Induced Senescence pathway
Signalling by NGF pathway
Toll Like Receptor 7/8 (TLR7/8) Cascade pathway
Signaling by EGFR in Cancer pathway
Downstream signaling of activated FGFR pathway
Regulation of HSF1-mediated heat shock response pathway
Neuronal System pathway
Signaling by VEGF pathway
Cytokine Signaling in Immune system pathway
Signaling by GPCR pathway
Innate Immune System pathway
Platelet activation, signaling and aggregation pathway
Toll Like Receptor 2 (TLR2) Cascade pathway
Toll-Like Receptors Cascades pathway
Axon guidance pathway
RAF/MAP kinase cascade pathway
Fc epsilon receptor (FCERI) signaling pathway
Signal Transduction pathway
MAP kinase activation in TLR cascade pathway
Post NMDA receptor activation events pathway
IRS-mediated signalling pathway
G-protein mediated events pathway
Cell Cycle pathway
Immune System pathway
VEGFR2 mediated cell proliferation pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events pathway
Insulin receptor signalling cascade pathway
M Phase pathway
Cellular Senescence pathway
Signaling by Interleukins pathway
VEGFA-VEGFR2 Pathway pathway
Signalling to ERKs pathway
NGF signalling via TRKA from the plasma membrane pathway
Cellular response to heat stress pathway
IRS-related events pathway
Mitotic Prophase pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Transmission across Chemical Synapses pathway
IGF1R signaling cascade pathway
Cell Cycle, Mitotic pathway
Prolonged ERK activation events pathway
Activated TLR4 signalling pathway
Nuclear Events (kinase and transcription factor activation) pathway
Senescence-Associated Secretory Phenotype (SASP) pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
MAPK targets/ Nuclear events mediated by MAP kinases pathway
TRIF-mediated TLR3/TLR4 signaling pathway
Oxidative Stress Induced Senescence pathway
Ca-dependent events pathway
Disease pathway
Signaling by Leptin pathway
FCERI mediated MAPK activation pathway
Hemostasis pathway
Toll Like Receptor 3 (TLR3) Cascade pathway
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation pathway
Toll Like Receptor 2 (TLR2) Cascade pathway
Innate Immune System pathway
Regulation of actin dynamics for phagocytic cup formation pathway
Oxidative Stress Induced Senescence pathway
Signaling by ERBB2 pathway
Cell Cycle, Mitotic pathway
Disease pathway
SHC-related events pathway
RAF/MAP kinase cascade pathway
Activation of the AP-1 family of transcription factors pathway
Hemostasis pathway
MAPK targets/ Nuclear events mediated by MAP kinases pathway
ERKs are inactivated pathway
Signaling by GPCR pathway
Recycling pathway of L1 pathway
Signaling by Insulin receptor pathway
Interleukin-2 signaling pathway
Ca-dependent events pathway
Cellular responses to stress pathway
MyD88 cascade initiated on plasma membrane pathway
Signaling by VEGF pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
ERK/MAPK targets pathway
Signaling by FGFR in disease pathway
Signaling by ERBB4 pathway
Signaling by SCF-KIT pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
SHC1 events in ERBB2 signaling pathway
Cytokine Signaling in Immune system pathway
Oncogene Induced Senescence pathway
VEGFR2 mediated cell proliferation pathway
phospho-PLA2 pathway pathway
Toll Like Receptor TLR1:TLR2 Cascade pathway
Cell Cycle pathway
CREB phosphorylation through the activation of Ras pathway
MAP kinase activation in TLR cascade pathway
Immune System pathway
Platelet activation, signaling and aggregation pathway
M Phase pathway
Toll Like Receptor 5 (TLR5) Cascade pathway
Post NMDA receptor activation events pathway
Toll Like Receptor TLR6:TLR2 Cascade pathway
SHC-mediated signalling pathway
Downstream signal transduction pathway
Downstream signaling of activated FGFR pathway
Negative regulation of FGFR signaling pathway
ERK activation pathway
SHC1 events in ERBB4 signaling pathway
Cellular Senescence pathway
Signalling to RAS pathway
Advanced glycosylation endproduct receptor signaling pathway
SHC1 events in EGFR signaling pathway
Toll Like Receptor 9 (TLR9) Cascade pathway
Signaling by EGFR pathway
Frs2-mediated activation pathway
Cellular response to heat stress pathway
Insulin receptor signalling cascade pathway
Golgi Cisternae Pericentriolar Stack Reorganization pathway
IRS-related events triggered by IGF1R pathway
IGF1R signaling cascade pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
VEGFA-VEGFR2 Pathway pathway
Axon guidance pathway
Fc epsilon receptor (FCERI) signaling pathway
Toll-Like Receptors Cascades pathway
Signalling to ERKs pathway
Signaling by Interleukins pathway
MyD88 dependent cascade initiated on endosome pathway
Senescence-Associated Secretory Phenotype (SASP) pathway
Signal transduction by L1 pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
L1CAM interactions pathway
Signalling by NGF pathway
Signaling by PDGF pathway
FRS2-mediated cascade pathway
Neuronal System pathway
Developmental Biology pathway
SOS-mediated signalling pathway
Activated TLR4 signalling pathway
IRS-related events pathway
NGF signalling via TRKA from the plasma membrane pathway
IRS-mediated signalling pathway
ERK2 activation pathway
Opioid Signalling pathway
Growth hormone receptor signaling pathway
ARMS-mediated activation pathway
Mitotic Prophase pathway
MyD88-independent cascade pathway
Signal Transduction pathway
GRB2 events in ERBB2 signaling pathway
Signaling by Leptin pathway
Prolonged ERK activation events pathway
Regulation of HSF1-mediated heat shock response pathway
Toll Like Receptor 7/8 (TLR7/8) Cascade pathway
Transmission across Chemical Synapses pathway
MyD88:Mal cascade initiated on plasma membrane pathway
Signaling by FGFR pathway
GRB2 events in EGFR signaling pathway
TRIF-mediated TLR3/TLR4 signaling pathway
Activation of NMDA receptor upon glutamate binding and postsynaptic events pathway
PLC beta mediated events pathway
FCERI mediated MAPK activation pathway
SHC-related events triggered by IGF1R pathway
G-protein mediated events pathway
RSK activation pathway
Signaling by EGFR in Cancer pathway
NCAM signaling for neurite out-growth pathway
Signalling to p38 via RIT and RIN pathway
Nuclear Events (kinase and transcription factor activation) pathway
DAP12 interactions pathway
DAP12 signaling pathway
Toll Like Receptor 10 (TLR10) Cascade pathway
Toll Like Receptor 4 (TLR4) Cascade pathway
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| KEGG |
Regulation of actin cytoskeleton pathway
mTOR signaling pathway pathway
GnRH signaling pathway pathway
Acute myeloid leukemia pathway
VEGF signaling pathway pathway
Fc epsilon RI signaling pathway pathway
Gap junction pathway
Colorectal cancer pathway
Non-small cell lung cancer pathway
ErbB signaling pathway pathway
TGF-beta signaling pathway pathway
Renal cell carcinoma pathway
MAPK signaling pathway pathway
Melanoma pathway
Axon guidance pathway
Thyroid cancer pathway
Adherens junction pathway
Endometrial cancer pathway
Long-term potentiation pathway
Bladder cancer pathway
Alzheimer's disease pathway
Glioma pathway
Insulin signaling pathway pathway
B cell receptor signaling pathway pathway
Prostate cancer pathway
Focal adhesion pathway
Long-term depression pathway
T cell receptor signaling pathway pathway
Toll-like receptor signaling pathway pathway
Type II diabetes mellitus pathway
Natural killer cell mediated cytotoxicity pathway
Chronic myeloid leukemia pathway
Pancreatic cancer pathway
Melanogenesis pathway
Fc gamma R-mediated phagocytosis pathway
Vascular smooth muscle contraction pathway
Dorso-ventral axis formation pathway
Neurotrophin signaling pathway pathway
Chemokine signaling pathway pathway
Prion diseases pathway
Pathways in cancer pathway
Progesterone-mediated oocyte maturation pathway
Aldosterone-regulated sodium reabsorption pathway
NOD-like receptor signaling pathway pathway
Oocyte meiosis pathway
Leishmaniasis pathway
Chagas disease (American trypanosomiasis) pathway
Osteoclast differentiation pathway
Shigellosis pathway
Toxoplasmosis pathway
Hepatitis C pathway
Endometrial cancer pathway
Axon guidance pathway
Bladder cancer pathway
Renal cell carcinoma pathway
ErbB signaling pathway pathway
TGF-beta signaling pathway pathway
Type II diabetes mellitus pathway
VEGF signaling pathway pathway
Insulin signaling pathway pathway
Acute myeloid leukemia pathway
Alzheimer's disease pathway
T cell receptor signaling pathway pathway
Melanogenesis pathway
Toll-like receptor signaling pathway pathway
Gap junction pathway
Colorectal cancer pathway
Thyroid cancer pathway
Fc epsilon RI signaling pathway pathway
Melanoma pathway
Natural killer cell mediated cytotoxicity pathway
GnRH signaling pathway pathway
Regulation of actin cytoskeleton pathway
MAPK signaling pathway pathway
Long-term potentiation pathway
Glioma pathway
Adherens junction pathway
mTOR signaling pathway pathway
Prostate cancer pathway
Long-term depression pathway
Chronic myeloid leukemia pathway
Non-small cell lung cancer pathway
Focal adhesion pathway
B cell receptor signaling pathway pathway
Pancreatic cancer pathway
Fc gamma R-mediated phagocytosis pathway
Chemokine signaling pathway pathway
Vascular smooth muscle contraction pathway
Prion diseases pathway
Neurotrophin signaling pathway pathway
Dorso-ventral axis formation pathway
Pathways in cancer pathway
Progesterone-mediated oocyte maturation pathway
Aldosterone-regulated sodium reabsorption pathway
NOD-like receptor signaling pathway pathway
Oocyte meiosis pathway
Leishmaniasis pathway
Osteoclast differentiation pathway
Toxoplasmosis pathway
Hepatitis C pathway
Chagas disease (American trypanosomiasis) pathway
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| INOH |
CD4 T cell receptor signaling pathway
IL-7 signaling pathway
JAK STAT pathway and regulation pathway
B cell receptor signaling pathway
Integrin signaling pathway pathway
EPO signaling pathway pathway
FGF signaling pathway pathway
GPCR Adenosine A2A receptor signaling pathway pathway
Insulin receptor signaling pathway
VEGF signaling pathway pathway
GPCR GroupI metabotropic glutamate receptor signaling pathway pathway
HGF signaling pathway pathway
EGF signaling pathway pathway
NGF signaling pathway pathway
IGF1 signaling pathway pathway
GPCR signaling pathway
TGF-beta signaling pathway
PDGF signaling pathway pathway
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| PID NCI |
Nongenotropic Androgen signaling
Ceramide signaling pathway
BMP receptor signaling
Presenilin action in Notch and Wnt signaling
Signaling events mediated by focal adhesion kinase
Class IB PI3K non-lipid kinase events
Fc-epsilon receptor I signaling in mast cells
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| Cross-References | |||||||||||||||||||||||||||||||||||||||||||||||||
| SwissProt | P46196 | ||||||||||||||||||||||||||||||||||||||||||||||||
| TrEMBL | F1MI27 | ||||||||||||||||||||||||||||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||||||||||||||||||||||||||||
| Entrez Gene | 327672 | ||||||||||||||||||||||||||||||||||||||||||||||||
| UniGene | Bt.109487 | ||||||||||||||||||||||||||||||||||||||||||||||||
| RefSeq | |||||||||||||||||||||||||||||||||||||||||||||||||
| HUGO | |||||||||||||||||||||||||||||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||||||||||||||||||||||||||||
| CCDS | |||||||||||||||||||||||||||||||||||||||||||||||||
| HPRD | |||||||||||||||||||||||||||||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||||||||||||||||||||||||||||
| EMBL | BC133588 DAAA02045719 Z14089 | ||||||||||||||||||||||||||||||||||||||||||||||||
| GenPept | AAI33589 CAA78467 | ||||||||||||||||||||||||||||||||||||||||||||||||
| RNA Seq Atlas | 327672 | ||||||||||||||||||||||||||||||||||||||||||||||||