InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PAPOLA

Summary

InnateDB Gene

IDBG-634303.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PAPOLA

Gene Name

Poly(A) polymerase alpha

Synonyms

PAPOLB

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004054

Encoded Proteins

IDBP-686108

Poly(A) polymerase alpha

IDBP-686114

Poly(A) polymerase alpha

IDBP-686115

Poly(A) polymerase alpha

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000090060:
The protein encoded by this gene belongs to the poly(A) polymerase family. It is required for the addition of adenosine residues for the creation of the 3'-poly(A) tail of mRNAs. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
The protein encoded by this gene belongs to the poly(A) polymerase family. It is required for the addition of adenosine residues for the creation of the 3\'-poly(A) tail of mRNAs. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 21:62980457-63032069

Strand

Forward strand

Band

Transcripts

ENSBTAT00000021001	ENSBTAP00000021001
ENSBTAT00000005300	ENSBTAP00000005300
ENSBTAT00000063150	ENSBTAP00000054531

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0003723	RNA binding
GO:0004652	polynucleotide adenylyltransferase activity
GO:0005524	ATP binding
GO:0016740	transferase activity
GO:0016779	nucleotidyltransferase activity
GO:0030145	manganese ion binding
GO:0046872	metal ion binding

Biological Process

GO:0000398	mRNA splicing, via spliceosome
GO:0006369	termination of RNA polymerase II transcription
GO:0006378	mRNA polyadenylation
GO:0006397	mRNA processing
GO:0031123	RNA 3'-end processing
GO:0043631	RNA polyadenylation