Version 5.4
Bos taurus Gene: BT.58492
Summary
InnateDB Gene IDBG-633849.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.58492
Gene Name mitochondrial Rho GTPase 2
Synonyms MIRO-2; MIRO2
Species Bos taurus
Ensembl Gene ENSBTAG00000004551
Encoded Proteins
IDBP-685591
mitochondrial Rho GTPase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000140983:
This gene encodes a member of the Rho family of GTPases. The encoded protein is localized to the outer mitochondrial membrane and plays a role in mitochondrial trafficking and fusion-fission dynamics. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:547440-552281
Strand Reverse strand
Band
Transcripts
ENSBTAT00000005979 ENSBTAP00000005979
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003924 GTPase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007264 small GTPase mediated signal transduction
GO:0019725 cellular homeostasis
GO:0047497 mitochondrion transport along microtubule
GO:0097345 mitochondrial outer membrane permeabilization
Cellular Component
GO:0005622 intracellular
GO:0005741 mitochondrial outer membrane
GO:0031307 integral component of mitochondrial outer membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000140983
View Gene Order
ENSMUSG00000025733
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11051
Rho GTPase cycle pathway
REACT_11044
Signaling by Rho GTPases pathway
REACT_111102
Signal Transduction pathway
REACT_206918
Signaling by Rho GTPases pathway
REACT_210090
Rho GTPase cycle pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1N6Q3
UniProt Splice Variant
Entrez Gene 352959
UniGene Bt.58492
RefSeq NM_178316
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057279
GenPept
RNA Seq Atlas 352959

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca