Version 5.4
Bos taurus Gene: FYB
Summary
InnateDB Gene IDBG-629944.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FYB
Gene Name FYN-binding protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001492
Encoded Proteins
IDBP-681385
FYN-binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000082074:
The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:35248388-35347535
Strand Forward strand
Band
Transcripts
ENSBTAT00000001953 ENSBTAP00000001953
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000082074
View Gene Order
ENSMUSG00000022148
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_6
KitReceptor pathway
NetPath_11
TCR pathway
REACTOME
REACT_12623
Generation of second messenger molecules pathway
REACT_23916
Signal regulatory protein (SIRP) family interactions pathway
REACT_111155
Cell-Cell communication pathway
REACT_12526
TCR signaling pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_230745
Immune System pathway
REACT_215628
Signal regulatory protein (SIRP) family interactions pathway
REACT_229531
Adaptive Immune System pathway
REACT_225768
Generation of second messenger molecules pathway
REACT_223082
Cell-Cell communication pathway
REACT_222648
TCR signaling pathway
KEGG
INOH
PID NCI
tcr_pathway
TCR signaling in naïve CD4+ T cells
Cross-References
SwissProt
TrEMBL A7YWJ7
UniProt Splice Variant
Entrez Gene 535347
UniGene Bt.103663
RefSeq NM_001105414 XM_005221607 XM_005221609 XM_005221610
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134622 DAAA02050584
GenPept AAI34623
RNA Seq Atlas 535347

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca