InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ELP3

Summary

InnateDB Gene

IDBG-629659.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ELP3

Gene Name

Elongator complex protein 3

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002730

Encoded Proteins

IDBP-681087

Elongator complex protein 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134014:
ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:10456058-10576397

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000003541

ENSBTAP00000003541

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003824	catalytic activity
GO:0004402	histone acetyltransferase activity
GO:0005515	protein binding
GO:0008080	N-acetyltransferase activity
GO:0008607	phosphorylase kinase regulator activity
GO:0016740	transferase activity
GO:0016746	transferase activity, transferring acyl groups
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006368	transcription elongation from RNA polymerase II promoter
GO:0016573	histone acetylation
GO:0030335	positive regulation of cell migration
GO:0045859	regulation of protein kinase activity

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0008023	transcription elongation factor complex
GO:0016591	DNA-directed RNA polymerase II, holoenzyme
GO:0033588	Elongator holoenzyme complex