InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cpt1b

Summary

InnateDB Gene

IDBG-262654.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cpt1b

Gene Name

carnitine palmitoyltransferase 1b, muscle

Synonyms

Cpt1; Cpt1-m; Cpti; Cpti-m; M-cpti

Species

Mus musculus

Ensembl Gene

ENSMUSG00000078937

Encoded Proteins

IDBP-262656

carnitine palmitoyltransferase 1b, muscle

IDBP-625745

carnitine palmitoyltransferase 1b, muscle

IDBP-625747

carnitine palmitoyltransferase 1b, muscle

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000205560:
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:89416405-89425863

Strand

Reverse strand

Band

Transcripts

ENSMUST00000109313	ENSMUSP00000104936
ENSMUST00000168879	ENSMUSP00000128188
ENSMUST00000165419
ENSMUST00000168376	ENSMUSP00000129786

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004095	carnitine O-palmitoyltransferase activity
GO:0005515	protein binding
GO:0016746	transferase activity, transferring acyl groups

Biological Process

GO:0006635	fatty acid beta-oxidation
GO:0008152	metabolic process
GO:0015909	long-chain fatty acid transport

Cellular Component

GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0016021	integral component of membrane
GO:0043231	intracellular membrane-bounded organelle