Mus musculus Gene: Rplp2 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-212230.6 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | Rplp2 | ||||||||||||||||||||||
Gene Name | ribosomal protein, large P2 | ||||||||||||||||||||||
Synonyms | 2700049I22Rik | ||||||||||||||||||||||
Species | Mus musculus | ||||||||||||||||||||||
Ensembl Gene | ENSMUSG00000025508 | ||||||||||||||||||||||
Encoded Proteins |
ribosomal protein, large P2
ribosomal protein, large P2
ribosomal protein, large P2
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177600:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 7:141447370-141451585 | ||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||
Band | F5 | ||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Peptide chain elongation pathway
Translation pathway
Eukaryotic Translation Termination pathway
Nonsense-Mediated Decay (NMD) pathway
Metabolism of proteins pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Cap-dependent Translation Initiation pathway
Eukaryotic Translation Initiation pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Eukaryotic Translation Elongation pathway
Formation of a pool of free 40S subunits pathway
Gene Expression pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
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KEGG |
Ribosome pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of a pool of free 40S subunits pathway
Eukaryotic Translation Termination pathway
Peptide chain elongation pathway
Eukaryotic Translation Elongation pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Viral mRNA Translation pathway
Eukaryotic Translation Initiation pathway
Influenza Infection pathway
Nonsense-Mediated Decay (NMD) pathway
Influenza Viral RNA Transcription and Replication pathway
Translation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Influenza Life Cycle pathway
Gene Expression pathway
Disease pathway
SRP-dependent cotranslational protein targeting to membrane pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Peptide chain elongation pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
Gene Expression pathway
Eukaryotic Translation Initiation pathway
Cap-dependent Translation Initiation pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Formation of a pool of free 40S subunits pathway
Translation pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Metabolism of proteins pathway
Nonsense-Mediated Decay (NMD) pathway
Eukaryotic Translation Termination pathway
Eukaryotic Translation Elongation pathway
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KEGG |
Ribosome pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | P99027 | ||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | 67186 | ||||||||||||||||||||||
UniGene | Mm.441503 Mm.469206 | ||||||||||||||||||||||
RefSeq | NM_026020 XM_006536229 | ||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | CCDS40187 | ||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
MGI ID | MGI:1914436 | ||||||||||||||||||||||
MGI Symbol | Rplp2 | ||||||||||||||||||||||
EMBL | AK002419 AK008344 AK010618 AK012402 AK012526 AK028140 AK028149 AK088737 AK134206 AK166774 BC012413 | ||||||||||||||||||||||
GenPept | AAH12413 BAB22086 BAB25616 BAB27066 BAB28217 BAB28297 BAC25768 BAC25777 BAC40539 BAE22051 BAE39010 | ||||||||||||||||||||||
RNA Seq Atlas | 67186 | ||||||||||||||||||||||